Brain
suggests
about
proteomiCS
Proteins are extremely important
in neuroscience, so BRAIN cannot neglect them. Proteome is a new word for an
old thing, that is the “protein complement encoding by a genome” according Marc
R. Wilkins who coined the term in 1994. The definition of proteomics varies
depending on whom you ask, but most researchers agree that it is the study of
the proteome, the collective body of proteins made by an organism’s cells and
tissues. What is new, of course, is the perspective, now that Human Genome
Project is completed and biotech is ready for the challenge.
(Terms ending in “-ome” and
“omics” are proliferating, visit
www.genomicglossaries.com/content/omes.asp)
The best thing to do, for knowing
more about proteins, remains visiting independent scientists in their labs, but
for knowing biotech’s “new thing”, you might visit these websites.
MSD Proteomics, Toronto,
www.mdsproteomics.com focuses on receptors and intracellular signaling.
SGX, San Diego,
www.stromix.com focuses
on protein structure of key targets within protein families.
CELERA, Rockville, Md,
www.celera.com focuses
on disease related proteins that could be targeted by drugs.
CELLZOME, Heidelberg, Germany,
www.cellzome.com focuses on cellular protein complexes and protein interactions.
HYBRIGENICS, Paris, France,
www.hybrigenics.com focuses
on drug targets.
CURAGEN, New Haven, Conn,
www.curagen.com
holds a patent on the yeast two-hybrid method
for outlining prot. networks.
GENEPROT, North Brunswick, NJ,
www.geneprot.com
second industrial-scale proteomics facility to
open in 2002 in NJ.
LARGE SCALE BIOLOGY, Vacaville,
CA,
www.lsbc.com
is building a linked family of comprehensive
databases of the human proteome.
MYRIAD, Salt Lake City,
www.myriad.com
focuses on enzymes and signaling circuits.
SYRRX,
San Diego,
www.syrrx.com focuses
on three-dimensional protein structures to discover new drugs.
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