FOLIC ACID AMOUNT AND THE PREVENTION OF NEURAL-TUBE DEFECTS
An interesting
correspondence in May 20 issue of New England Journal of Medicine (Folic Acid and the
prevention of neural tube defects. NEJM 350, 2209-2211, 2004) reviews a previous
evaluation published in the same journal. The author states that in his Perspective
article on folic acid and the prevention of neural-tube defects, Wald (NEJM, Jan 8, 2004
issue)
overestimates the amount needed to achieve folate levels that provide
protection against neural-tube defects.