FOLIC ACID AMOUNT AND THE PREVENTION OF NEURAL-TUBE DEFECTS

 

An interesting correspondence in May 20 issue of New England Journal of Medicine (Folic Acid and the prevention of neural tube defects. NEJM 350, 2209-2211, 2004) reviews a previous evaluation published in the same journal. The author states that in his Perspective article on folic acid and the prevention of neural-tube defects, Wald (NEJM, Jan 8, 2004 issue) overestimates the amount needed to achieve folate levels that provide protection against neural-tube defects.

 

BM&L-May 2004