PRINCIPLES OF MOLECULAR, CELLULAR AND MEDICAL NEUROBIOLOGY
Eight Edition, 2012.
Scott T. Brady (editor-in-chief), George J. Siegel (editor-in-chief emeritus); R. Wayne Albers, Donald L. Price (editors); Joyce Benjamins, Stephen Fisher, Alison Hall, Nicolas Bazan, Joseph Coyle, Sangram Sisodia (associate editors).
Published by Elsevier/Academic Press on account of American Society for Neurochemistry.
“This Eight Edition of Basic Neurochemistry: Principles of Molecular, Cellular and Medical Neurobiology encompasses 40 years of progress in neurochemistry since its first edition, Basic Neurochemistry: Principles of Molecular, Cellular and Medical Aspects. This seems an appropriate time to consider the progress of neurochemistry and of this book. To make this brief, we will consider only two topics, both featured prominently in this edition: neurodegeneration and neuroimmunology. When the first edition was being written, the neurochemistry of neurodegenerative disease was in its infancy, while neuroimmunology didn’t exist as a discipline”.
“In contrast, when Basic Neurochemistry first appeared in 1972, immunology and neuroscience occupied different worlds. Little overlap was seen beyond the damage to neurons during inflammation due to infection and autoimmune episodes such as multiple sclerosis. Indeed the brain was thought to be isolated from the immune system by the blood brain barrier, creating an immunologically privileged domain. When this barrier was breached, the nervous system was inevitably damaged. As described in one of the new chapters added to this edition, we now understand that the nervous system plays an important role in regulating the immune system and immune responses”.
A detailed presentation of the book was made by the President of our National Italian Society (see Italian pages of Brain, Mind & Life website).