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BASIC NEUROCHEMISTRY PRINCIPLES OF MOLECULAR, CELLULAR AND MEDICAL
NEUROBIOLOGY Eight Edition, 2012. Scott
T. Brady (editor-in-chief), George J.
Siegel (editor-in-chief emeritus); R. Wayne Albers, Donald L.
Price (editors); Joyce Benjamins, Stephen Fisher, Alison Hall, Nicolas Bazan, Joseph Coyle, Sangram Sisodia (associate
editors). Published by Elsevier/Academic
Press on account of American Society for Neurochemistry. From Preface. “This Eight
Edition of Basic Neurochemistry: Principles
of Molecular, Cellular and Medical Neurobiology encompasses 40 years of
progress in neurochemistry since its first edition, Basic Neurochemistry: Principles of Molecular, Cellular and Medical Aspects.
This seems an appropriate time to consider the progress of neurochemistry and
of this book. To make this brief, we will consider only two topics, both
featured prominently in this edition: neurodegeneration and neuroimmunology.
When the first edition was being written, the neurochemistry of
neurodegenerative disease was in its infancy, while neuroimmunology didn’t
exist as a discipline”. “In contrast, when
Basic Neurochemistry first appeared
in 1972, immunology and neuroscience occupied different worlds. Little overlap
was seen beyond the damage to neurons during inflammation due to infection and
autoimmune episodes such as multiple sclerosis. Indeed the brain was thought to
be isolated from the immune system by the blood brain barrier, creating an
immunologically privileged domain. When this barrier was breached, the nervous
system was inevitably damaged. As described in one of the new chapters added to
this edition, we now understand that the nervous system plays an important role
in regulating the immune system and immune responses”. A detailed presentation of the book was made by the
President of our National Italian Society (see Italian pages of Brain, Mind
& Life website).
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