Brain Mind & Life International has promoted an updating on the neurobiology of addiction organizing among its members several debates on the more controversial issues. The event originated from the focus devoted to basic neuroscience of addiction by Nature Neuroscience (Neurobiology of Addiction. Nature Neuroscience 8, 1427-1489, 2005).

The focus contain a series of specially commissioned reviews and perspectives on the neurobiology of drug abuse, decision making and habit formation, as well as a commentary on how these basic science insights should guide public policy on addiction and its treatment. Each feature has been the starting point for a BM&Lís member presentation. The full content is listed below:


1. Neurobiology of addiction. 

2. The neuroscience of addiction.

3. Neurobiology of addiction: treatment and public policy ramifications.

4. The role of neuroadaptations in relapse to drug seeking.

5. How do we determine which drug-induced neuroplastic changes are important?

6. Plasticity of reward neurocircuitry and the 'dark side' of drug addiction.

7. Is there a common molecular pathway for addiction?

8. Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction.

9. Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective.

10. Nicotine addiction and comorbidity with alcohol abuse and mental illness. 

11. Laboratory models of alcoholism: treatment target identification and insight into mechanisms.

12. Neural systems of reinforcement for drug addiction: from actions to habits to compulsion.



BM&L-December 2005